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Application of High-throuphput Drug Sensitivity in the precise treatment of liver cancer

Application of High-throuphput Drug Sensitivity in the precise treatment of liver cancer

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900028488
Enrollment
Unknown
Registered
2019-12-22
Start date
2019-12-13
Completion date
Unknown
Last updated
2020-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver cancer

Interventions

Control Group:The drug treatment plan was made by reference to the results of high-throughput drug sensitivity test.
Control Group:Use An empirical drug protocol based on the guidelines

Sponsors

First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-70 years; 2. Preoperative clinical data, examination information, imaging information for the primary liver cancer patients; 3. A patient who has a complete or partial resection of a liver tumor; 4. First-time detection of liver cancer or recurrence of liver cancer; 5. Postoperative examination revealed one of the following: (1) Hepatocellular Carcinoma; (2) Cholangiocarcinoma; (3) Mixed Cell Carcinoma of liver.

Exclusion criteria

Exclusion criteria: 1. Combined with other malignant tumors; 2. Due to the small size of liver cancer tissue, it is impossible to obtain enough samples for primary tumor cell culture; 3. The primary Hepatoma cells could not be obtained because of the contamination of the specimens caused by various factors such as sampling, transportation and culture; 4. Accompanied by cardiovascular and cerebrovascular, kidney, endocrine system, hematopoiesis and other serious diseases; 5. Pregnant and lactating women and those who have recently prepared for pregnancy; 6. Patients with severe hypertension, systemic circulatory failure and DIC that are difficult to correct with medication; 7. Unable or unwilling to cooperate because of neurological or mental illness.

Design outcomes

Primary

MeasureTime frame
Overall Survival;Disease-free survival;progression-free-survival;Time to progression;Time to treatment failure;Local control rate in June and December;Tumor Marker;

Countries

China

Contacts

Public ContactShi Zhengrong

First Affiliated Hospital of Chongqing Medical University

shizr@hospital.cqmu.edu.cn+86 15111997815

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026