gonarthrosis
Conditions
Interventions
periarticular injection group (PAI):periarticular local infiltration anesthesia
intraarticular injection group (IAI):intraarticular local infiltration anesthesia
control group:none
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Selected patients who planned to undergo total knee arthroplasty; 2. Aged 50-80 years, ASA grades II-III; 3. voluntarily sign the informed consent; 4. Normal communication and learning ability.
Exclusion criteria
Exclusion criteria: 1. Knee replacement caused by trauma; 2. Allergic to the drugs required in the study; 3. There are contraindications for nerve block; 4. History of severe sinus bradysis < 50 / min, pathological sinus node syndrome, 2-degree type 2 atrioventricular block or severe arrhythmia affecting hemodynamic stability, cardiac insufficiency or heart failure; 5. A history of opioid use; 6. Neurological or psychiatric complications (clear sequelae of cerebral infarction, dementia, etc.). 7. Failed preoperative screening of MoCA
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the proportion of rescue analgesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| the length of hospital;sleep quality;Postoperative nausea and vomiting;the first time for rescue analgesia;the dose of rescue analgesics;the first time to walk with a walker;postoperative pain scores;postoperative delirium; | — |
Countries
China
Contacts
Public ContactGuang-Hong Xu
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed