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Study on repetitive transcranial magnetic stimulation promoting upper limb motor recovery in acute stroke patients

Study on repetitive transcranial magnetic stimulation promoting upper limb motor recovery in acute stroke patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900028355
Enrollment
Unknown
Registered
2019-12-19
Start date
2019-05-01
Completion date
Unknown
Last updated
2020-01-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Group A:1 Hz rTMS over the contralesional primary motor cortex (M1) and then 10HZ stimulation over the ipsilesional M1
Group B:contralesional sham stimulation and then 10HZ stimulation over the ipsilesional M1
Group C:contralesional real 1 Hz rTMS and then ipsilesional sham stimulation

Sponsors

the First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Onset time <2 weeks; Aged 18-80 years old; CT or diffusion weighted magnetic resonance imaging (DWI) confirmed the presence of ischemic stroke; MRI lesions were located in the blood supply area of internal carotid artery; Adverse lateral limb movement; Muscle strength of the affected upper limb is grade 4/5; Neglect, epilepsy; Sign the informed consent.

Exclusion criteria

Exclusion criteria: Do not use in patients with metal foreign body inside or outside the skull; Do not use pacemakers, medical pumps or cochlear implants, or increased intracranial pressure.Do not use in patients with recurrent or severe headache;High frequency strong stimulation has the risk of causing convulsion. High frequency strong stimulation is prohibited for patients with a history of epilepsy or a family history of epilepsy. Other diseases of the nervous or mental system; The cognitive dysfunction can't cooperate with the examination; serious aphasia or apraxia; Unable to complete the interview.

Design outcomes

Primary

MeasureTime frame
A multi-modal fMRI;

Secondary

MeasureTime frame
motor evoked potential;Motor function index;

Countries

China

Contacts

Public ContactQi Fang

Department of Neurology, the First Affiliated Hospital of Soochow University

fangqi_008@126.com+86 13606213892

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026