Ulcer after Endoscopic Submucosal Dissection
Conditions
Interventions
Group 1:Polaprezinc + Esomeprazole
Group 2:Esomeprazole
Sponsors
Beijing Tsinghua Chang Geng Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Comply with the indications for ESD surgery; (2) Aged 18-70 years, male:female=1:1; (3) blood coagulation function is normal; (4) Voluntarily participate in this research.
Exclusion criteria
Exclusion criteria: (1) Those who have severe complications after gastric ESD or do not reach a curative resection need supplementary surgery; (2) Pregnant and lactating women, and those who may become pregnant and prepare for pregnancy during clinical trials; (3) The patient also has other serious organic diseases that affect the evaluation of this study, such as severe liver disease, heart disease, kidney disease, malignant tumor and alcoholism disease; (4) Those who need to take antiplatelet and NSAIDS drugs for a long time; (5) Those who used antiulcer drugs outside the prescribed period during the trial; (6) Allergic reactions to Polyprezinc and Esmeprazole; (7) Inability to act autonomously and fail to express their main complaints correctly, such as mental illness, severe neurosis, and cannot cooperate with this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ulcer healing rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of verrucous process in the base of terminal ulcer, the incidence of delayed bleeding after operation and the rate of symptom relief after operation; | — |
Countries
China
Contacts
Public ContactJiang Bo
Beijing Tsinghua Chang Geng Hospital
Outcome results
None listed