Gastrointestinal Factors Associated With Delirium in ICU Patients Undergoing Cardiac Surgery

Gastrointestinal Risk Factors and Biomarkers Research in Delirious Patients With Cardiac Surgery: a Prospective Cohort Nested Case-Control Study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900028300

Enrollment

Unknown

Registered

2019-12-18

Start date

2020-01-01

Completion date

Unknown

Last updated

2020-04-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Delirium

Interventions

None listed

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: The study will include adult patients (>=18 years) admitted to the ICU who undergo elective and emergency cardiac surgeries with CPB.

Exclusion criteria

Exclusion criteria: The study will exclude patients who have a sustained Richmond Agitation and Sedation Scale (RASS) score -4 or -5 throughout the ICU admission (indicating coma), have no CAM-ICU assessment records, and patients who have major auditory or visual disorders or are unable to understand Chinese/Cantonese. Patients will have a detailed screening to exclude dementia, delirium (CAM) or cognitive impairment based on patients or family members reports, capacity assessments, and medical record reviews. Patients with pregnancy will be excluded too. The study is going to be conducted in Nanfang hospital affiliated to southern medical university, a teaching hospital in China. All patients will receive standardized cardiac surgical operation and perioperative care with existing protocols at Nanfang hospital, including general anesthesia and ICU care.

Design outcomes

Primary

Measure	Time frame
incidence of post-cardiac surgery delirium in ICU;	—

Secondary

Measure	Time frame
Delirium duration;Delirium type;Severity of delirium;ICT stay;Hospital Mortality;	—

Countries

China

Contacts

Public ContactLiu Kexuan

Department of Anesthesiology, Nanfang Hospital, Southern Medical University

liukexuan705@163.com+86 13710684096

Outcome results