amnestic type mild cognitive impairment, aMCI
Conditions
Interventions
Sponsors
The People's Hospital of Bao'an Shenzhen
Eligibility
Sex/Gender
All
Age
55 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. aged 55–75 years old; 2. memory complaint, provided by the patient or family; 3. memory impairment for age; 4. right-handed; 5. Montreal Cognitive Assessment (MoCA) score <=26; 6. Clinical Dementia Rating Scale (CDR) of 0.5 points, or total decline scale (GDS) of 2 to 3; 7. Normal daily living ability.
Exclusion criteria
Exclusion criteria: 1. other diseases that cause cognitive decline(e.g., stroke, vascular, Parkinson's disease, traumatic, medical); 2. they had a Hachinski Ischaemic score of >4 or/and Hamilton Depression Scale (HAMD) >8 points; 3. People with claustrophobia and disorders such as deafness, language impairment and blindness could not perform MRI and cognitive function test; 4. had contraindications for TMS, such as implanting metal objects in the body, installation of electronic devices, pacemakers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TMS-EEG;P300; | — |
Secondary
| Measure | Time frame |
|---|---|
| MoCA;EEG; | — |
Countries
China
Contacts
Public ContactZHU Fen
The People's Hospital of Bao'an Shenzhen
Outcome results
None listed