Guillian-Barre syndrome
Conditions
Interventions
Two groups:Methylprednisolone versus IVIG
Sponsors
Shenzhen Second People's Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 100 Years
Inclusion criteria
Inclusion criteria: 1. Combined with Asbury or Cornblath diagnostic criteria, and refer to the diagnostic criteria of China 2010 guidelines, the diagnosis as GBS; 2. TRF-GBS or progressive GBS patients with symptomatic fluctuations at the same time, TRF-GBS diagnostic criteria reference: 1991 Kleyweg diagnostic criteria, the specific manifestations are as follows: (1) After GBIG patients were treated with IVIG or PE, the Hughes score of the patients improved by at least 1 point compared with before treatment, and then the Hughes score increased within at least 1 point within 8 weeks of onset, or the condition was stable after the treatment was greater than 1 point. Hughes score appeared at least 1 point worse than before; (2) Patients with GBS who have undergone IVIG or PE treatment; patients who have improved their Hughes score by less than 1 point and continue to progress.
Exclusion criteria
Exclusion criteria: 1. Patients who give up examination and treatment within 5 days of admission; 2. Patients with acute or chronic peripheral neuropathy due to other reasons cannot be excluded; 3. Patients who refuse to use IVIG or PE within 2 weeks of onset, or have been treated with hormones; 4. Have been retreated with IVIG, PE or hormones in two weeks after onset.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hughes score; | — |
Countries
China
Contacts
Public ContactZhou Yanxia
Shenzhen Guangdong Province, the Second People's Hospital
Outcome results
None listed