Acute Ischemic Stroke
Conditions
Interventions
Endovascular treatments:Endovascular treatments
Sponsors
The Second Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Aged >=18 years; 2. Acute ischemic stroke; 3. NIHSS score >= 4 points; 4. Imaging confirmation (CTA/MRA-DSA) intracranial aorta infarct: intra-cervical artery (T/L), brain artery M1/M2 segment, brain front artery A1/A2, base artery, vertebral artery V4, brain post-arterial P1; 5. ASPECT (front loop) or PC-ASPECT (back loop) score >= 6 points; 6. The endovascular treatments include arterial thrombosis, mechanical thrombosis, angioplasty, etc. (within 24 hours of the onset to the puncture time cycle recommended within 24 hours (incidence of more than 6h, to meet dawn or DEFFUSE-3 research selection criteria), after the cycle is built within 24 hours, the over-time window is determined by the researcher's imaging assessment); 7. The patient or the patient's legal representative can and is willing to sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. mRS score > 2; 2. Intracranial hemorrhage diseases: cerebral hemorrhage, subcavity hemorrhage of the cobwebs, etc.; 3. There is a history of clotting disorders, systemic bleeding, a history of platelet reduction or a history of neutrophil reduction; 4. Renal insufficiency, blood creatinine increase (greater than the normal maximum 2 times); 5. With severe cardiopulmonary disease, the researchers do not consider it suitable to participate in this study; 6. Patients with a life expectancy of less than 3 months or who are unable to complete the study for other reasons; 7. DSA check taboo, severe contrast agent allergy or iodine contrast agent absolute taboo; 8. Women of childbearing age, pregnant or lactating women who are negative in pregnancy tests but refuse to take effective contraception; 9. The researcher cannot complete due to mental disorders, cognitive or emotional disorders; Other researchers thought it was uncomfortable for patients in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NIHSS;mRS; | — |
Countries
China
Contacts
Public ContactWu Yanfeng
The Second Affiliated Hospital of Nanjing Medical University
Outcome results
None listed