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Efficacy analysis of infusion of different vasopressors to prevent hypotension in cesarean section from affecting umbilical artery pH

Efficacy analysis of infusion of different vasopressors to prevent hypotension in cesarean section from affecting umbilical artery pH

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900028150
Enrollment
Unknown
Registered
2019-12-13
Start date
2019-12-10
Completion date
Unknown
Last updated
2019-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension

Interventions

1:norepinephrine
3:Metaraminol

Sponsors

Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists physical status I and II, who had nonlaboring, normotensive parturients with term singleton pregnancy with baseline systolic BP within the range 90 to 140 mmHg scheduled for elective caesarean section

Exclusion criteria

Exclusion criteria: Exclusion criteria were American Society of Anesthesiologists physical status of 3 or higher, preexisting or pregnancy-induced hypertension, known fetal abnormality or intra-uterine growth restriction, known cardiovascular or cerebrovascular disease, thrombocytopenia, coagulopathy, any medical contraindication to combined spinal–epidural anesthesia, known allergy to phenylephrine or norepinephrine or Metaraminol, weight less than 50 kg or greater than 100 kg, height less than 140 cm or greater than 180 cm, inability or refusal to give informed consent, and age less than 18 yr.Women were excluded from subsequent analysis if combined spinal–epidural (CSE) anaesthesia not established, administration of epidural drugs was required during the period until delivery of the fetus, or severe shivering made non-invasive blood pressure monitoring unreliable.

Design outcomes

Primary

MeasureTime frame
umbilical artery pH;

Secondary

MeasureTime frame
Maternal outcomes (Nausea and Vomiting; Bradycardia;hypotension; Hypertension; Dizzy; Dyspnea);Fetal outcomes (the outcomes of the analysis of umbilical artery and vein blood gas; Apgar score at 1 and 5 min);hemodynamics;

Countries

China

Contacts

Public ContactGang Chen

The Central Hospital of Lishui City

chengang120@hotmail.com+86 13757118681

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026