acute ST segment elevation myocardial infarction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. the first onset of acute myocardial infarction; 2. the blood flow at culprit coronary artery after PCI meets TIMI 3; 3. sinus rhythm and > 100 times/min; 4. systolic pressure <=110mmHg; 5. echocardiography showed left ventricular ejection fraction <=45%; 6. All patients received standard doses of dual antiplatelet therapy (aspirin + ADP receptor inhibitor) and statin.
Exclusion criteria
Exclusion criteria: 1. the blood flow at culprit coronary artery after PCI didn't reach TIMI3; 2. complicated with non-culprit lesions requiring intervention during this hospital stay; 3. sustained rapid atrial/ventricular arrhythmia; 4. sick sinus syndrome, II to III degree atrioventricular block; 5. IABP implantation; 6. moderate or severe anemia; 7. hyperthyroidism or hypothyroidism; 8. previous history of myocardial infarction; 9. complicating mechanical complications after myocardial infarction (ventricular septum perforation/papillary muscular insufficiency/cardiac rupture); 10. complicated with heart valvular disease or other diagnosed heart disease; 11. hemorrhagic disease; 12. Severe liver dysfunction (Child-Pugh score >=10 points) or end stage of renal failure (Creatinine clearance <15ml/min); 13. malignant tumor; 14. poor adherence; 15. using the sedative drugs; 16. involved in other clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cardiac output;heart rate;stroke volume;mean arterial pressure;Brachial arterial blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| NT-proBNP;LVEF; | — |
Countries
China
Contacts
First Affiliated Hospital of Xi'an Jiaotong University