Prevention of spinal anesthesia-induced hypotension after cesarean delivery with different loading doses of norepinephrine: a randomized, double-blind, controlled trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900028119

Enrollment

Unknown

Registered

2019-12-12

Start date

2020-01-15

Completion date

Unknown

Last updated

2019-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal anesthesia-induced hypotension in cesarean delivery

Interventions

1:0.05ug/kg load dose

2:0.10ug/kg load dose

3:0.15ug/kg load dose

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Combined lumbar and epidural anesthesia under the elective cesarean section of a full-term pregnancy

Exclusion criteria

Exclusion criteria: There are contraindications of lumbar anesthesia, serious liver and kidney diseases, abnormal coagulation, thyroid function, birth process, age less than 20 years old, weight less than 50kg or more than 100kg, height less than 140cm or more than 170cm, systolic pressure less than 100mmhg, oral monoamine oxidase inhibitors, antipsychotics, antidepressants, thrombotic diseases

Design outcomes

Primary

Measure	Time frame
Blood pressure;	—

Secondary

Measure	Time frame
heart rate;time;Nausea and vomiting;Anesthesia plane;Apgar score;	—

Countries

China

Contacts

Public ContactLv Wenyuan

Qilu Hospital of Shandong University (Qingdao)

lwyjerry@163.com+86 18561811387

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026