Neonatal respiratory distress syndrome
Conditions
Interventions
Control Group: Invasive or non-invasive ventilation
Experimental group 1:HHHFNC
Experimental group 2:NCPAP
Experimental group 3:NIPPV
Experimental group 4:NHFV
Sponsors
Guangdong Women and Children Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Fetal age <=37 weeks; 2. Those who meet the RDS Diagnostic Standards for Practical Neonatology (4th edition); 3. With the guardian's informed consent of the infants; 4. The infant's guardian agrees to receive pulmonary surfactant replacement therapy or mechanically assisted ventilation if necessary.
Exclusion criteria
Exclusion criteria: 1. Congenital malformations of the respiratory system, complex congenital heart disease, severe intrauterine infection, severe instability of the circulatory system, congenital genetic metabolic diseases and chromosomal diseases; 2. Family members refuse to participate; 3. Those who fail to complete the study and cannot provide complete data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood gas analysis;intubation in 72 hours;intubation in 72 h-7d;oxygen time;Ventilation time;Bronchopulmonary dysplasia;Retinopathy of prematurity;Necrotizing enterocolitis;Air leak;Intraventricular hemorrhage;Number of deaths;Patent ductus arteriosus; | — |
Countries
China
Contacts
Public ContactGao Weiwei/Chen Jia
Guangdong Women and Children Hospital
Outcome results
None listed