Lung transplantation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Received single or double lung transplantation at Shanghai Pulmonary Hospital after 2015; 2. BOS has not yet occurred; 3. Aged 18-80 years old; 4. Expected survival time exceeds 3 months; 5. The patient volunteered to participate in the study, and was able to cooperate with obtaining alveolar tank lotion, stool, and peripheral blood specimens, and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who have difficulty swallowing or have gastrointestinal obstruction; 2. Patients who have a previous history of gastrointestinal surgery; 3. After evaluation, the researcher believes that the study is not good for the patient or is not suitable for other conditions in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BOS;Allograft Injury; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gut microbiome;lung microbiome;Fecal metabolomics;Immune factor; | — |
Countries
China
Contacts
Shanghai Pulmonary Hospital