Effect of multi-mode preanalgesia on gastrointestinal dysfunction and postoperative outcome in patients undergoing laparoscopic colorectal surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900028049

Enrollment

Unknown

Registered

2019-12-08

Start date

2020-01-01

Completion date

Unknown

Last updated

2019-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer, colon cancer

Interventions

Experimental group:Transabdominal muscle plane block was performed before anesthesia induction + Flurbiprofen 1mg/kg was given before skin cutting + Oxycodone was given at 0.1mg/kg before skin cutting

control group:Sufentanil was given at 0.1ug/kg before peeling + Before the operation, flurbiprofen was given 1mg/kg + Sufentanil was administered at 0.1ug/kg before surgery + TAPB was performed postop

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Laparoscopic colorectal surgery was performed at an appropriate time; 2. ASA I ~ III level; 3. Aged 18 to 65 years; 4. BMI18kg/m2-35 kg/m2.

Exclusion criteria

Exclusion criteria: 1. Refused to participate in this study; 2. Had performed colorectal surgery; 3. Had a history of chemoradiotherapy; 4. Contraindications to nsaids; 5. Severe neurological and psychiatric diseases; 6. Severe cardiovascular diseases; 7. Severe respiratory diseases; 8. Local infection of TAPB puncture site; 9. Below primary education level.

Design outcomes

Primary

Measure	Time frame
I-FEED;Complications of other organs after operation;	—

Secondary

Measure	Time frame
VAS;Index of postoperative rehabilitation progress;TNF-a;	—

Countries

China

Contacts

Public ContactLiu Chao-Lei

Department of anesthesiology, the Second Hospital of Hebei Medical University

verna521@163.com+86 13582618357

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026