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The analgestic effect and safety of intravenous hydromorphone on postoperative analgesia in children after surgery.

The analgestic effect and safety of intravenous hydromorphone on postoperative analgesia in children after surgery.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900028042
Enrollment
Unknown
Registered
2019-12-08
Start date
2019-11-30
Completion date
Unknown
Last updated
2019-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative analgesia in children

Interventions

1:concentration of hydromorphone2-3ug/kg*h
2:concentration of hydromorphone3-4ug/kg*h
3:concentration of hydromorphone4-5ug/kg*h
4:concentration of sufentanil 0.08ug/kg*h
5:concentration of morphine 20ug/kg*h

Sponsors

Children's Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: From November 2019 to November 2020, children who underwent elective correction of congenital heart disease under cardiopulmonary bypass at the Children's Hospital of Chongqing Medical University had normal growth and development without liver and kidney dysfunction.

Exclusion criteria

Exclusion criteria: Patients with liver and kidney dysfunction, neurological developmental disorders, those who need to use vasoactive drugs before surgery, those who have undergone mechanical ventilation, and those who have a history of surgery.

Design outcomes

Primary

MeasureTime frame
lactic acid;blood glucose;cortisol;facial pain scale;CRIES scale;COMFORT-B scale;RAMSAY scale;Respiratory rate;Heart rate;oxygen saturation;Mean arterial pressure;Adverse reactions;The number of temporary additional sedatives;Average extubation time;

Countries

China

Contacts

Public ContactFeng Xu

Children's Hospital of Chongqing Medical University

Xufeng9899@163.com+86 023-63664659

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026