postoperative pain and immune function
Conditions
Interventions
Experimental group:dexmedetomidine and ketorolac applied for postoperative PCA
Sponsors
Tangshan Maternity and Child Healthcare Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) American Society of Anesthesiologists (ASA) physical status I or II; (2) Those scheduled to undergo elective laparoscopic surgery for cervical cancer; (3) Those who agree to use postoperative analgesia pump; (4) Those who sign informed consent.
Exclusion criteria
Exclusion criteria: (1) severe cardiac or respiratory diseases, or significant renal or hepatic impairment, or immune disorders; (2) history of immunosuppressive therapy (chemotherapy or radiation); (3) history of chronic pain, or analgesic drug abuse; (4) high levels of C-reactive protein (CRP), or leukocytosis (>10,000/mL) prior surgery; (5) participants with hypersensitivity to the study medication; (6) participants enrolled in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative VAS scores;serum levels of IL-2;serum levels of IL-6;serum levels of VEGF; | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of postoperative side effects;consumption of PCIA pump; | — |
Countries
China
Contacts
Public ContactLi Ao
Tangshan Maternity and Child Healthcare Hospital
Outcome results
None listed