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A randomized controlled clinical study of combined trabeculectomy and trabeculectomy alone in young patients with stge-weber syndrome with complex superficial vascular abnormalities of the sclera

A randomized controlled clinical study of combined trabeculectomy and trabeculectomy alone in young patients with stge-weber syndrome with complex superficial vascular abnormalities of the sclera

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900027972
Enrollment
Unknown
Registered
2019-12-07
Start date
2020-01-01
Completion date
Unknown
Last updated
2020-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glaucoma

Interventions

Combined Trabeculotomy Group:Combined Trabeculotomy
Simple Trabeculotomy Group:Simple Trabeculotomy

Sponsors

Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 4 Years

Inclusion criteria

Inclusion criteria: 1. Younger than 4 years old; 2. The diagnosis of secondary glaucoma in SWS must be met. The diagnostic criteria are as follows (at least the following two points should be met on the premise of the presence of wine stains on the affected face and face): (1) IOP of the affected eye> 21 mmHg Contralateral elevation > 6 mmHg; (2) cup-disk ratio of the affected eye> 0.5 or cup-disk ratio of the affected eye increased> 0.2; (3) corneal diameter of the affected eye:> 11 mm at birth,> 12 mm within 12 months of age Any age> 13 mm; (4) suffering from corneal edema or rupture of the elastic layer. 3. The type of scleral surface vessels is "composite scleral surface vessels network".

Exclusion criteria

Exclusion criteria: 1. The eye condition is highly suspected to be glaucoma caused by other causes such as primary congenital glaucoma, A-R syndrome or Peter's abnormality; 2. Other eye diseases or congenital abnormalities, such as congenital cataract, retinopathy of prematurity, primitive vitreous hyperplasia syndrome, outer exudative retinopathy, congenital no iris, albinism, retinoblastoma, etc 3. History of internal eye surgery and trauma; 4. Refusing to sign informed consent; 5. Those who cannot complete the 2-year follow-up.

Design outcomes

Primary

MeasureTime frame
intraocular pressure;cup to disk ratio;

Countries

China

Contacts

Public ContactGuo Wenyi

Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine

wyguo@163.com+86 13816880563

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026