Irritable bowel syndrome of constipation type
Conditions
Interventions
Single arm:Linaclotide
Sponsors
Department of Gastroenterology, the Second Affiliated Hospital of the Army Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged >= 18, and <= 65 years; 2. Unlimited for men and women; 3. Patients with constipation type irritable bowel syndrome were diagnosed; 4. Voluntarily accept and abide by the experimental program, and receive reexamination and follow-up on time; 5. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating women, or female patients with family planning during the study period; 2. Patients with mental diseases; 3. Those who have taken probiotics or antibiotics one month before the study; 4. Patients who have done intestinal cleaning in the past 2 weeks; 5. Patients who are allergic to the drugs used in this study; 6. Participated in other drug research in the first three months; 7. Patients with digestive system tumor; 8. Patients with gastrointestinal operation history; 9. Patients with inflammatory bowel disease; 10. Patients with intestinal obstruction; 11. Patients with gastrointestinal bleeding; 12. Those who are unwilling to participate in the trial, refuse to sign informed consent or have poor compliance in comprehensive judgment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes of gut flora composition; | — |
Secondary
| Measure | Time frame |
|---|---|
| Differences in intestinal flora between patients and healthy people; | — |
Countries
China
Contacts
Public ContactYang Shiming
83 Xinqiao Main Street, Shapingba District, Chongqing
Outcome results
None listed