Coronary heart disease, diabetes
Conditions
Interventions
Healthy control group:N/A
coronary heart disease with type 2 diabetes mellitus group:N/A
Sponsors
Zhejiang Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 90 Years
Inclusion criteria
Inclusion criteria: The age ranges from 40 to 80 years. Diabetes was defined as type 2 diabetes, onset at >= 30 years of age, with no history of ketoacidosis. Coronary heart disease is defined as at least 50% stenosis of one or more coronary arteries or major coronary arteries on coronary angiography.
Exclusion criteria
Exclusion criteria: (1) unstable CAD (CAD symptoms changed in the first 60 days); (2) history of acute coronary syndrome and heart failure; (3) abnormal ecg results, namely pathological Q wave, ischemic ST wave or complete left bundle branch block; (4) valvular disease, dilated/hypertrophic cardiomyopathy; (5) hyperthyroidism or hypothyroidism; (6) cancer or end-stage kidney or liver disease; (7) various infectious and inflammatory diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| calcitonin gene-related peptide (CGRP);substance P (SP);somatostatin (SOM);tumor necrosis factor (TNF-a);interleukin (IL-1ß);intercellular adhesion molecule (ICAM-1);chemokine (MCP-1); | — |
Secondary
| Measure | Time frame |
|---|---|
| endothelin (ET);prostacyclin (PGI2);Nitric Oxide (NO); | — |
Countries
China
Contacts
Public ContactWang Lihong
Zhejiang Provincial People's Hospital
Outcome results
None listed