kidney failure
Conditions
Interventions
Group 2:Anticoagulation with citric acid
Group 1:Heparin anticoagulation
Sponsors
CQ Southwest Hospital Nephrology Department
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 70 years old, male or female; 2. Acute or chronic renal failure requiring hemodialysis; 3. Voluntarily participate in this clinical trial and sign the informed consent form; 4. Risk of bleeding or active bleeding.
Exclusion criteria
Exclusion criteria: 1. Recent (7 days) use of antiplatelet drugs and/or use of anticoagulant drugs (other than anticoagulant drugs necessary for hemodialysis); 2. Patients with severe hypoxemia; 3. Patients with refractory hypocalcemia; 4. Patients with severe alkalosis that cannot be corrected; 5. Anemia patients with hemoglobin less than 50g/L; 6. Abnormal liver function (ALT and/or AST > upper limit of 1.5 times), severe hematologic disease, malignant tumor or other underlying disease; 7. Alcohol or substance abusers; 8. Have mental illness cannot cooperate; 9. Allergic constitution, known to be allergic to the test drug (sodium citrate) and its excipients or heparin Pregnant, recently pregnant, nursing women; 10. Participants in other clinical trials in the past 1 month; 11. The researchers concluded that there were other conditions that were not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| analysis of blood gas;electrolyte;ACT; | — |
Secondary
| Measure | Time frame |
|---|---|
| urine routine;blood routine;liver function;coagulation function; | — |
Countries
China
Contacts
Public ContactPan Xie
CQ Southwest Hospital Nephrology Department
Outcome results
None listed