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Medical record based on study: population pharmacokinetic/pharmacodynamic study of vancomycin in in the treatment of preterm neonates using the Stochastic Approximation Expectation Maximization (SAEM) algorithm

Medical record based on study: Population pharmacokinetic/pharmacodynamic study of vancomycin in in the treatment of preterm neonates using the Stochastic Approximation Expectation Maximization (SAEM) algorithm

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900027919
Enrollment
Unknown
Registered
2019-12-04
Start date
2020-01-01
Completion date
Unknown
Last updated
2019-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infection

Interventions

Case series:N/A

Sponsors

Nanjing Maternity and Child Health Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients included in the study were admitted to neonatal intensive care unit (NICU) after birth. When vancomycin treatment started, patient's postmenstrual age (PMA, the sum of gestational age (GA) and postnatal age (PNA)) was less than 37 weeks. Gender was not limited; 2. All patients were treated with vancomycin for at least 3 days, and at least one reliable vancomycin serum concentration was assayed; 3. Patients had complete clinical data.

Exclusion criteria

Exclusion criteria: 1. Vancomycin was not used to treat infection during clinical therapy; 2. Patients had missing basic information and clinical data were incomplete; 3. Patient's PMA was beyond 37 weeks when vancomycin treatment started; 4. The duration of vancomycin treatment was less than 3 days; 5. Vancomycin serum concentration was not obtained or lower than the quantitative limit during the treatment.

Design outcomes

Primary

MeasureTime frame
vancomycin serum concentration;demographics;Blood biochemistry;Blood routine;Etiological examination;MIC measurement;

Countries

China

Contacts

Public ContactZHE TANG

Nanjing Maternity and Child Health Care Hospital

tjj870520@hotmail.com+86 18252009631

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 24, 2026