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Effects of nalbuphine and ketorolac preventive analgesia on acute pain and early recovery after endoscopic sinus surgery: a prospective, randomized, controlled trial

Effects of nalbuphine and ketorolac preventive analgesia on acute pain and early recovery after endoscopic sinus surgery: a prospective, randomized, controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900027898
Enrollment
Unknown
Registered
2019-12-03
Start date
2019-11-27
Completion date
Unknown
Last updated
2019-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Analgesia after endoscopic sinus surgery

Interventions

Group T:Ketorolac tromethamine
Group N:nalbuphine

Sponsors

First Affiliated Hospital of He'nan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 56 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 65 years; Body mass index (BMI) 19 to 28kg / m2; 2. ASA grades I to II; 3. Selective nasal endoscopic surgery under general anesthesia; 4. Select patients with deviated nasal septum; 5. Sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. severe heart, lung, liver and kidney dysfunction, and abnormal coagulation function; 2. History of allergies to opioids and NSAIDs; 3. Combined with mental illness and recent history of taking opioids; 4. long-term drinking or drug abuse history; 5. History of gastrointestinal ulcer; 6. The patient refused to participate.

Design outcomes

Primary

MeasureTime frame
VAS;—

Contacts

Public ContactJing Liu

First Affiliated Hospital of He'nan University

1050342740@qq.com+86 18438602833

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026