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Clinical study on the effect of transjugular portal shunt on intestinal microecology

Clinical study on the effect of transjugular portal shunt on intestinal microecology

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900027886
Enrollment
Unknown
Registered
2019-12-02
Start date
2020-01-01
Completion date
Unknown
Last updated
2019-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

portal hypertension

Interventions

Tips group:N/A

Sponsors

Department of Gastroenterology, Xinqiao Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. aged 18-70 years, gender not limited. 2. All cases were in line with the diagnostic criteria for cirrhosis by referring to the 2015 guidelines for prevention and treatment of chronic hepatitis b and the unified standards proposed by Anthony. 3. Gastroscope assessment for severe varicose vein bypass to internal jugular vein for the hydrodynamic intervention patients (evaluation standard reference 2015 liver cirrhosis portal hypertension stomach esophagus varicosity burst hemorrhage treatment expert consensus), but there is no history of active bleeding (no history, hematemesis, black and endoscopic found no bleeding, spray blood, blood clots).

Exclusion criteria

Exclusion criteria: 1. Patients confirmed by CT or MRI, histopathology and other examinations that cirrhosis complicated with liver cancer or histopathology confirmed the presence of gastric cancer, ancreatic cancer or other malignant tumors. 2. Bucca syndrome. 3. Liver cirrhosis complicated with systemic lupus erythematosus, crohn's disease, ulcerative colitis and other inflammatory bowel diseases. 4. A history of taking antibiotics or probiotics in the last month. 5. Patients after splenectomy or splenic artery embolization. 6. A history of gastrointestinal or gastrointestinal surgery. 7. Patients with other undesirable factors (severe constipation or diarrhea) considered by the researchers.

Design outcomes

Primary

MeasureTime frame
gut microbiota;

Countries

China

Contacts

Public ContactShiming Yang

Department of Gastroenterology, Xinqiao Hospital

shimingyang@yahoo.com+86 13228686589

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026