Epidural-related maternal fever
Conditions
Interventions
Simple ropivacaine group:Epidural administration of Ropivacaine alone
Ropivacaine combined with Sufentanil group:Epidural administration of Ropivacaine combined with Sufentanil
Ropivacaine combined with Dexmedetomidine group:Epidural administration of Ropivacaine combined with Dexmedetomidine
Sponsors
Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Suitable for vaginal delivery, voluntary labor analgesia,aged 20 ~ 35 years; 2. Gestation ranges from 37 to 41 weeks,singletons, cephalic presentation, height:150-175cm, weight:55-85kg; 3. ASAI-II?; 4. Normol fetal heart and movement.
Exclusion criteria
Exclusion criteria: 1. History of severe cardiopulmonary disease, bradycardia; 2. Morbid obesity, severe preeclampsia, macrosomia, multiple births, etc.; 3. History of cesarean section or induction of labor; 4. Contraindications for epidural analgesia; 5. Diabetes, hyperthyroidism, hypothyroidism and other metabolic diseases; 6. Basal body temperature >= 38 degree C; Prophylactic use of antibiotics; 7. Patients enrolled in other clinical trials in the last three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maternal eardrum temperature; | — |
Secondary
| Measure | Time frame |
|---|---|
| Basic vital signs (heart rate, blood pressure, oxygen saturation) and fetal heart rate at each time point;Serum levels of IL - 6, TNF - ? concentration;Epidural sensory blockade level;Labor time;Analgesic time;Apgar score at 1 and 5min;Incidence of maternal nausea, vomiting, itching and respiratory depression; | — |
Countries
China
Contacts
Public ContactLiu Su
Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed