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Clinical study of nalbuphine combined with ropivacaine for epidural labor analgesia

Clinical study of nalbuphine combined with ropivacaine for epidural labor analgesia

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900027847
Enrollment
Unknown
Registered
2019-11-30
Start date
2019-12-01
Completion date
Unknown
Last updated
2019-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

labor pain

Interventions

Group N:Nalbuphine combined with Ropivacaine
Group S:Sufentanil combined with Ropivacaine

Sponsors

Qingdao Women and Children's Hospital, Qingdao University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1) The American anesthesiologists Association (ASA) physical status II and III; (2) Aged 20~40 years; (3) Height is 150 to 175 cm; (4) BMI 18.5~35kg/m2; (5) Single station, head presentation; (6) The indexes of heart, liver, kidney and blood were all in normal range; (7) Obtain informed consent and volunteer to join according to GCP regulations.

Exclusion criteria

Exclusion criteria: (1) Important organs include primary diseases, such as hyperthyroidism, cardiopulmonary diseases, neuromuscular diseases, etc.; (2) Mentally or physically handicapped patients; (3) A history of alcohol or drug abuse is suspected or true; (4) Allergic constitutions such as allergies to two or more drugs or foods, or known allergies to nalbuphine and sufentanil; (5) Epidural anesthesia is contraindicated.

Design outcomes

Primary

MeasureTime frame
the time elapsed to the patient's first request for further analgesia;Onset time of analgesia;Neonatal neuroadaptability score;

Secondary

MeasureTime frame
First lactation time;

Countries

China

Contacts

Public ContactChen Zuolei

Qingdao Women and Children's Hospital, Qingdao University

chenzuolei_qd@163.com+86 18561967939

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026