bladder cancer
Conditions
Interventions
Treatment group:en bloc transurethral resection
Control group:conventional TURBT + secondary transurethral resection
Sponsors
The Second Hospital of Tianjin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 80 years old, Male or female; 2. All cases were pathologically diagnosed with non-muscle-invasive urothelial carcinoma and without other components (eg: adenocarcinoma, squamous cell carcinoma, sarcoma); 3. All patients undergo standard TURBT or en bloc transurethral resection by senior physicians and receive routine intravesical instillation; (BCG); 4. Tumor number <= 3, tumor size <= 3cm; 5. Pathologically diagnosed as non muscular invasive bladder urothelial carcinoma which is defined as Moderate or High risk; 6. Patient is able to understand the trail, sign the informed consent and are willing to get regular follow-up.
Exclusion criteria
Exclusion criteria: 1. Lymph node or distant metastasis; 2. Tumor grade and stage can not be accurately assessed; 3. Visible tumor were not completely removed at the first TURBT due to tumor location, tumor number, carcinoma in situ, obturator nerve reflex and other reasons; 4. The confirmed or suspected bladder perforation; 5. The clinical data is incomplete; 6. Combined with other serious diseases and life expectancy <2 years; 7. Pregnancy or lactating women; 8. Can not understand the content of the trail and sign the informed consent; 9. With upper urinary tract urothelial carcinoma, low-risk bladder urothelial carcinoma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression rate;Survival rate; | — |
Countries
China
Contacts
Public ContactHu Hailong
The Second Hospital of Tianjin Medical University
Outcome results
None listed