COPD
Conditions
Interventions
1:argon knife lung volume reduction under thoracoscope
Sponsors
Integrated Hospital of Traditional Chinese Medicine,Southern Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of COPD according to China national guideline for the diagnosis and treatment of Chronic Obstructive Pulmonary Disease (revised edition 2013) 2.The diameter of either one bulla or the sum of multiple continuous bullae is greater than 6cm with over-ventilation in lesion site under HRCT.The average CT value during inhale phase is less than -960Hu.The lesion site is surrounded with compressed lung tissue. 3. Between 18 and 75 years old. 4.Patients who are fully informed for the current study and willingness to cooperate with the follow-up.
Exclusion criteria
Exclusion criteria: 1. PO2<60mmHg with low liter flow rate of nasal O2 ( <= 3L/min); 2. AECOPD; 3. Pleural adhesions or pleural thickening; 4. coagulation disorders; 5. PLT < 40 x 10^9/L; 6. Severe infection; 7. Severe heart disease, arrhythmia or cardiac insufficiency; 8. Systemic disease or cancer; 9. Pregnant women; 10. Patients get involved in other clinical trials or completed the previous clinical trials within 90 days; 11. Other occasions when considered by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chest CT scan; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary Function;Six-minute walk;blood gas analysis; | — |
Countries
China
Contacts
Public ContactQixiao Feng
Integrated Hospital of Traditional Chinese Medicine,Southern Medical University
Outcome results
None listed