Stanford A aortic dissection
Conditions
Interventions
intervention group one :lung recruitment with continuous positive airway pressure
intervention group two:fixed inspiratory pressure with stepwise rising PEEP
intervention group three:increase inspiratory pressure and PEEP both
intervention group four:fixed tidal volumn with stepwise rising PEEP
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Acute type A aortic dissection; 2. The operation of ascending aorta + total aortic arch replacement + stent elephant trunk implantation was performed after deep hypothermic circulation arrest; 3. oxygenation index PaO2/FiO2<150.
Exclusion criteria
Exclusion criteria: 1. Acute type A aortic dissection; 2. The operation of ascending aorta + total aortic arch replacement + stent elephant trunk implantation was performed after deep hypothermic circulation arrest; 3. oxygenation index PaO2/FiO2<150; 4. History of heart surgery or thoracotomy; 5. Diabetics who need insulin to control their blood sugar; 6. Chronic obstructive pulmonary disease, pulmonary bullae, pleural effusion; 7. Coronary artery bypass grafting or valve replacement during the same period; 8. Preoperative cardiac insufficiency (EF<0.45); 9. severe anemia (hemoglobin<70g/L); 10. hepatic and renal dysfunction 11. Hemodynamic instability (systolic pressure<90mmHgVasoactive drugs are difficult to maintain or require IABP support); 12. Postoperative nervous system complication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| success rate of lung recruitment;incidence of hypotension; | — |
Secondary
| Measure | Time frame |
|---|---|
| mechanical ventilation time;staying time in ICU;levels of Inflammatory Factors; | — |
Countries
China
Contacts
Public ContactZeng Xiaochun
The First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed