Bladder Carcinoma
Conditions
Interventions
single-arm:1
single-arm:2
Sponsors
Shenzhen Luohu People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Initial diagnosis, middle-high-risk urothelial carcinoma patients undergoing transurethral resection or neoadjuvant chemotherapy before electrification; 2. Life expectancy is greater than 5 years and above; 3. Immunohistochemistry confirmed the high expression of a-glucosidase 2; 4. After the communication, I am willing to participate in this test, promise to take the medicine according to the doctor's advice, and can follow up and communicate in time.
Exclusion criteria
Exclusion criteria: 1. Any of the following conditions: those with immunodeficiency or damage (such as AIDS patients) who are using immunosuppressive drugs or radiation therapy; those with fever and acute infectious diseases, including active tuberculosis, or receiving anti-tuberculosis Therapist; accompanied by severe chronic cardiovascular or cerebrovascular disease or chronic kidney disease; 2, combined with other cancer patients; 3. Those who have received chemotherapy, radiotherapy or immunotherapy in the past 4 weeks (except for intravesical infusion chemotherapy immediately after surgery); 4. Known or suspected bladder perforation during surgery; 5. severe urethral stricture can not be placed into the cystoscope; 6. pelvic CT examination or full physical examination found tumor metastasis; 7. Low immune function, acquired, congenital immunodeficiency disease, or history of organ transplantation; 8. suffering from severe cardiovascular and cerebrovascular diseases, such as myocardial infarction, severe / unstable angina, coronary / peripheral artery bypass surgery, symptomatic congestive heart failure, cerebrovascular accident or transient ischemic attack, or pulmonary embolism Those who cannot tolerate TURBT surgery; 9. there are obvious major internal organ dysfunction, such as: creatinine > 1.5 times the upper limit of the normal range, AST, ALT, total bilirubin > 1.5 times the upper limit of the normal range; 10. The fever temperature exceeds 38 degree C, and there are obvious active infections that can affect clinical trials such as acute pneumonia, active tuberculosis, and subjects with severe urinary tract infections; 11. Opioids or alcohol dependent individuals are known; 12. Apparent gastrointestinal reactions after taking miglitol; 13. The investigator believes that there may be any situation that increases the risk of the subject or interferes with the performance of the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rathe;Relapse free survival; | — |
Countries
China
Contacts
Public ContactWu Song
Shenzhen Luohu People's Hospital (Shenzhen University Third Affiliated Hospital)
Outcome results
None listed