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Clinical Study of Piezosurgery on Promoting Post-extraction Clotting in Patients with Dual Antiplatelet Therapy

Clinical Study of Piezosurgery on Promoting Post-extraction Clotting in Patients with Dual Antiplatelet Therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900027766
Enrollment
Unknown
Registered
2019-11-27
Start date
2020-01-01
Completion date
Unknown
Last updated
2019-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-extraction bleeding

Interventions

1:dental extraction by piezosurgery among DAPT patients
2:dental extraction by turbine handpiece among DAPT patients
3:dental extraction by piezosurgery among normal population
4:dental extraction by turbine handpiece among normal population

Sponsors

Shanghai Stomatological Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: DAPT patients (age> 50 years old, aspirin 100mg / d + clopidogrel 75mg / d, treatment time> 6 months); blood routine, activated partial thromboplastin time (APTT), prothrombin time (PT) , Thrombin time (TT), fibrinogen (FIB) and other detection values are within the normal range; TEG's MA value (Figure 2) is lower than the normal lower limit (50mm), indicating non-DAPT drug resistance; Maxillary canine (residual crown, subgingival stump, tooth fracture line with large defect area reaching subgingival).

Exclusion criteria

Exclusion criteria: Bleeding disorders; receiving other treatments that can lead to a higher risk of bleeding (low coagulation); uncontrolled hypertension, heart disease, diabetes, liver and kidney disease; other conventional contraindications to tooth extraction.

Design outcomes

Primary

MeasureTime frame
clotting level;max magnitude;

Countries

China

Contacts

Public ContactLu Mengmeng
lumengmeng19810428@126.com+86 13611736568

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026