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Interaction between dietary choline intake and choline-metabolising genetic polymorphisms on risk of gestational diabetes mellitus and pregnant outcome

Interaction between dietary choline intake and choline-metabolising genetic polymorphisms on risk of gestational diabetes mellitus and pregnant outcome

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900027764
Enrollment
Unknown
Registered
2019-11-27
Start date
2019-12-30
Completion date
Unknown
Last updated
2019-12-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gestational diabetes mellitus

Interventions

Case series:NA

Sponsors

The Seventh People's Hospital Affiliated to Shanghai University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Pregnant1 women at 24-28 weeks of pregnancy and 18-50 years of age, visiting the Seventh People's Hospital Affiliated to Shanghai University of Chinese Medicine for GDM screening; 2. Ability to read, understand and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnant women diagnosed as type I or type II diabetes before pregnancy; 2. Currently, drugs that affect blood sugar are used, such as metformin and glucocorticoids; 3. Currently, drugs that affect blood choline metabolites, such as essential, are used; 4. Pregnant women with severe heart, brain, liver and kidney diseases, gestational thyroid disease, and placenta previa; 5. HIV-positive, women who have thalassemia, cystic fibrosis, systemic lupus erythematosus, other autoimmune diseases, and history of chemotherapy.

Design outcomes

Secondary

MeasureTime frame
blood biochemical indexes;Neonatal outcomes;Maternal blood Insulin level;Incidence of gestational hypertention;

Primary

MeasureTime frame
Incidence of gestational diabetes Birth weight;Blood choline and its metabolites;choline-metabolising genetic polymorphisms;maternal outcomes;

Countries

China

Contacts

Public ContactYuhong Liu

The Seventh People's Hospital Affiliated to Shanghai University of Chinese Medicine

liuyuhong0121@126.com+86 13916645497

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026