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The Effect and Mechanism of Intermittent Theta Burst Stimulation on Post-stroke Depression

The Effect and Mechanism of Intermittent Theta Burst Stimulation on Post-stroke Depression

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900027686
Enrollment
Unknown
Registered
2019-11-23
Start date
2019-12-01
Completion date
Unknown
Last updated
2019-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke Depression

Interventions

Sponsors

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine , Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Consistent with the western diagnostic criteria of stroke, CT or MRI showed clear signs of neurological damage; (2) Hamilton Depression Scale (HAMD) > 8 points; (3) Both male and female aged 30 to 80 years old; (4) Right hand; (5) Consciousness; (6) Understand, agree to participate in the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Other brain diseases; (2) Severe systemic diseases; (3) Severe aphasia or severe cognitive impairment , severe hearing impairment, visual impairment or severe language understanding disorder may affect the assessment due to other reasons; (4) History of depression and other mental illnesses before stroke occurs; (5) Addiction to drugs, alcohol or other substances; (6) Metal implants in the body; history of epilepsy or history of seizures; direct genus has a history of epilepsy and other contraindications for transcranial magnetic stimulation; (7) History of skull fractures and/or severe head injuries, head and/or brain surgery; (8) Pregnancy (positive HCG test), lactating women.

Design outcomes

Primary

MeasureTime frame
HAMD;

Secondary

MeasureTime frame
blood biochemical index;Neuroimaging index;

Countries

China

Contacts

Public ContactChunlei Shan

ShangHai University of Traditional Chinese Medicine

shanclhappy@163.com+86 13816215058

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026