gastric cancer
Conditions
Interventions
Case series:Nil
Sponsors
Bangwei Cao
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. In patients with advanced gastric cancer who have failed to be diagnosed by pathology and/or cytology, at least one evaluable target lesion with a scale measurement of >= 1.0 cm; 2. aged >= 18 years old; 3. ECOG physical status score is 0-2; 4. Life expectancy after the start of administration of the study drug >= 12 weeks; 5. The function of each organ meets the following criteria: AST, ALT = 1500 /uL; platelets >= 80,000/uL, hemoglobin >= 80 g/L; 6. Informed consent has been signed for the name and time, indicating that the patient has been informed of all relevant matters prior to enrollment; 7. Patients using anticoagulants must meet the following conditions within 7 days of treatment: INR < 1.5 and APTT < 1.5 ULN.
Exclusion criteria
Exclusion criteria: 1. Currently receiving other anti-tumor treatments (including radiotherapy); 2. Renal insufficiency: creatinine clearance 2+ patients should be measured 24h urine collection, and must be confirmed protein / 24 hours 150 mmHg and / or diastolic blood pressure > 100 mmHg) or clinically significant (such as active) cardiovascular disease (6 months before enrollment), myocardial infarction (6 months before enrollment)), unstable angina, NYHA grade II or higher congestive heart failure, or severe arrhythmia can not be controlled by drugs or have potential effects on trial treatment; 5. History or examination results indicate the presence of hereditary bleeding tendency or coagulopathy; 6. Severe or unhealed wounds, peptic ulcers or (healed incomplete) fractures; 7. Active gastrointestinal bleeding, gastrointestinal perforation or abdominal abscess; 8. Pregnant or lactating patients; 9. Patients with severe medical problems, such as cardiac dysfunction or related history such as myocardial infarction or severe arrhythmia history.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DCR; | — |
Countries
China
Contacts
Public ContactBangwei Cao
Beijing Friendship Hospital, Capital Medical University
Outcome results
None listed