postoperative neurocognitive disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged >65 years old; 2. Patients undergoing general anesthesia for non-cardiac surgery; 3. The patient had no previous history of mental illness or language dysfunction; 4. Preoperative cognitive function assessment met clinical criteria; 5. The estimated duration of the operation >2h.
Exclusion criteria
Exclusion criteria: 1. ASA-v or VI; 2. Clinically definite diagnosis of coagulation dysfunction, severe heart failure, hepatorenal insufficiency and severe infectious diseases; 3. Moderate and above pulmonary dysfunction; 4. Suspect or have a history of alcohol or drug abuse; 5. A history of cerebral infarction and cerebral hemorrhage.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative delayed neurocognitive recovery; | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative delirium;postoperative complication; | — |
Countries
China
Contacts
Xiangya Hospital, Central South University