preterm
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Born in our hospital from November 2019 to May 2020; premature babies born in 30-34 weeks of gestation; weight between 1500-3000g
Exclusion criteria
Exclusion criteria: Family history of depression or mental illness; family history of congenital brain development disorder; congenital malformation, chromosomal abnormalities; moderate to severe hypoxic ischemic encephalopathy, grade III and IV intraventricular hemorrhage (IVH), periventricular leukomalacia(PVL); congenital genetic metabolic disease, cardiac insufficiency, digestive tract malformation, endocrine abnormalities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain function connection; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intestinal microbiome;Cognitive developmental level; | — |
Countries
China
Contacts
Zhejiang University School of Medicine