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PDX model building and multi-omics screening of pancreatic cancer

PDX model building and multi-omics screening of pancreatic cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900027646
Enrollment
Unknown
Registered
2019-11-22
Start date
2019-11-30
Completion date
Unknown
Last updated
2019-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pancreatic cancer

Interventions

ampullary cancer:no
control group:no

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) the histopathology and (or) cytology diagnosis of pancreatic cancer, including: 1) the EUS or CT guided puncture biopsy; Fall off 2) ascites cytology; 3) probe under laparoscopy or laparotomy biopsy; (2) pancreatic cancer pathological types of ductal adenocarcinoma (including glands squamous carcinoma, mucinous carcinoma [] mucous sex of cystic carcinoma, liver samples, medullary carcinoma, adenocarcinoma, undifferentiated carcinoma, signet ring cell carcinoma with broken bone giant cell anaplastic carcinoma and other special subtype) and pathological types include around ampulla carcinoma group except the pancreatic head carcinoma of ampulla surrounding tissues malignant tumor (end of the common bile duct and duodenum papillary adenocarcinoma etc).

Exclusion criteria

Exclusion criteria: 1. tumor TNM staging in stage III or IV or generally poor patients; 2. parenteral nutrition or part of the patients with enteral nutrition; 3. chronic alcoholism and severe liver and kidney disease; 4. chemotherapy or radiotherapy patients; 5. have confirmed with the gut microbes causal correlation condition or disease patients (type II diabetes, sclerosis of arterial congee appearance, obesity (BMI > 30), liver cirrhosis, colorectal cancer, rheumatoid arthritis). 6. may affect the gut microbes species and metabolic disease, cholecystitis, appendicitis, various intestinal inflammatory diseases); 7. are taking affect gut microbes species and metabolism of drugs in patients with drugs (antibiotics, metformin, anti-rheumatism medicine and other may affect drug); 8. large gastrointestinal surgery patients; 9. diarrhea or constipation patients.

Design outcomes

Primary

MeasureTime frame
gene;metabolites;

Countries

China

Contacts

Public ContactBING PENG

West China Hospital, Sichuan university

pengbing84@hotmail.com+86 18980601481

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026