Pancreatic pseudocyst with infection
Conditions
Interventions
experimental group:Minimally invasive open external drainage
control group:Open debridement lavage
Sponsors
Department of Pancreatic Surgery, Center of digestive & vascular medicine, The First Affiliated Hospital of Xinjiang Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Obtain informed consent from the subject; 2. The clinical cure has passed the acute phase, and the condition deteriorates again after the condition is stable, and the patient cannot eat or the fever lasts for more than 1 week; 3. Enhanced CT showed "bubble sign" in intraperitoneal or peripancreatic lesions; 4. Exclude pulmonary infection, catheter infection, urinary tract infection and other non-pancreatic fever or deterioration; 5. Within 7 days before the operation, there was sufficient liver and kidney function, appropriate laboratory indicators (after treatment) : neutrophils >=1500/mm3, PLT>=50x10^9/L, and serum ALB>=28g/L. TBIL < 2mg/dL, ALT and AST < 5 times normal value, Bun and Cr < 1.5 times normal value, INR < 1.7 or PT extension < 4s.
Exclusion criteria
Exclusion criteria: 1.Congestive heart failure > New York heart association (NYHA) grade 2; 2. Uncontrolled high blood pressure; 3. A history of human immunodeficiency virus (HIV) infection; 4. Renal failure or insufficiency, requiring hemodialysis or peritoneal dialysis; 5. Severe active clinical infection (> level 2, nci-ctcae version 4.0); 6. Except for upper gastrointestinal bleeding or clear tendency of gastrointestinal bleeding within 4 weeks before surgery; 7. Subjects who are pregnant or breast-feeding; 8. Patients who had major surgery 4 weeks before the trial or who had not yet recovered from the side effects of such surgery; 9. Patients diagnosed with pancreatic neoplasms, such as cystadenoma (those who had been cured 3 years earlier could be included).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| POPF;Postoperative biliary fistula;Postoperative intestinal fistula;postoperative complication;Incidence of infection;Average length of stay; | — |
Countries
China
Contacts
Public ContactXinjian XU
The First Affiliated Hospital of Xinjiang Medical University
Outcome results
None listed