colorectal cancer
Conditions
Interventions
Gold Standard:Pathological examination
Index test:New Caicon Panel
Sponsors
Digestive System Department, Nanfang Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria of the subjects are as follows: 1) patients with histologically diagnosed colorectal cancer; 2) any MMR protein (MLH1, MSH2, MSH6, PMS2) lack of expression; 3) sufficient samples of tumor tissues and normal tissues (adjacent normal tissues/peripheral blood) meeting the requirements for examination (see "4. Sample collection" below); 4) agree to provide basic information, clinical information and family tumor history information.
Exclusion criteria
Exclusion criteria: 1) genetic mutations of related genes have been clearly inherited by blood relatives; 4.1.3 subject withdrawal criteria: 1) the sample cannot be tested successfully due to too little or other reasons, and the sample cannot be provided or refused again; 2) in principle, the sample that has been tested cannot be withdrawn. If I want to withdraw due to my strong will, I will withdraw. 4.2 criteria for inclusion, exclusion and withdrawal of blood relatives in pedigree verification
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| New caicon panel sequencing; | — |
Countries
China
Contacts
Public ContactBaoping wu
Southern Medical University
Outcome results
None listed