Alzheimer's disease
Conditions
Interventions
Gold Standard:NIA-AA Alzheimer's Criteria(2011)
Index test:A 
beta 
40, 
A 
42, 
T-Tau, 
p-Tau, 
NFL, 
CHI3L1, 
H-FABP, 
TREM2, 
VILIP, 
Sponsors
Army Medical University Daping Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Age 55 or older (including 55 years old); 2) Willing to take venous blood collection and lumbar puncture; 3) Cognitive unimpaired (control group) Meets the diagnostic criteria for AD issued by the 2011 NIA-AA (AD group); 4) Willing to participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Intracranial infection or systemic infection; 2) Cardiac diseases such as severe coronary heart disease, cardiac insufficiency, and atrial fibrillation; 3) Severe liver and kidney dysfunction; 4) Severe blood system diseases; 5) Central nervous system diseases such as acute stroke, intracranial tumor, and multiple sclerosis; 6) Advanced systemic malignant tumors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Aß40;Tau;Aß42;p-Tau;NFL;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactWang Yanjiang
Army Medical University Daping Hospital
Outcome results
None listed