sepsis
Conditions
Interventions
Gold Standard:Clinical outcome
Index test:the 
expression 
of 
EZH2 
on 
the 
Sponsors
Shanghai East Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1, age: >= 18 years; 2, a sepsis patient visiting the Shanghai East Hospital: in accordance with the definition of sepsis in "Sepsis 3.0", which is, sepsis is a life-threatening organ dysfunction caused by the imbalance of the host infection response 3. For patients with unknown organ dysfunction status or organ dysfunction before infection, the baseline SOFA score is set to 0, and the post-infection SOFA score >= 2 is used as the clinical diagnostic criteria for organ dysfunction. 4. Informed consent.
Exclusion criteria
Exclusion criteria: 1. Acute and chronic inflammatory diseases; 2. Along with other diseases, such as: tumors, kidney diseases, autoimmune diseases, etc.; 3. Currently participating in or participating in other clinical trials within one month; 4. Alcohol or drug dependence in the past 5 years; 5. Suffering from mental illness, can not achieve informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EZH2;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactTang Lunxian
Department of Internal Emergency Medicine and Critical Care, Shanghai East Hospital (South), Tongji University
Outcome results
None listed