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The optimal dose of nalbuphine preventive analgesia for laparoscopic cholecystectomy

The optimal dose of nalbuphine preventive analgesia for laparoscopic cholecystectomy

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1900027609
Enrollment
Unknown
Registered
2019-11-21
Start date
2019-11-28
Completion date
Unknown
Last updated
2019-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laparoscopic cholecystectomy

Interventions

Group 1:Intravenous injection of nalbuphine 0.1 mg/kg 15 minutes before induction of anesthesia
Group 2:Intravenous injection of nalbuphine 0.2 mg/kg 15 minutes before induction of anesthesia
Group 3:Intravenous injection of nalbuphine 0.3 mg/kg 15 minutes before induction of anesthesia

Sponsors

The Affiliated Huaian Hospital of Xuzhou Medical University, Huai'an Second Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: ASA I-II, patients aged 18-65 years undergoing laparoscopic cholecystectomy, Sign informed consent.

Exclusion criteria

Exclusion criteria: 1. history of chronic pain and history of long-term analgesics; 2. history of drug addiction and history of opioid allergy; 3. severe hypertension (systolic blood pressure >=180mmHg; diastolic blood pressure >=110mmHg); 4. severe liver and kidney disease and coagulation function.

Design outcomes

Primary

MeasureTime frame
Numerical Rating Score ;Extubation time;recovery time;

Countries

China

Contacts

Public ContactJun Wang

The Affiliated Huaian Hospital of Xuzhou Medical University, Huai'an Second Hospital

18051361436@163.com+86 15298668999

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026