Correlation among blood pressure variability, cerebral blood flow and white matter lesions

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR1900027605

Enrollment

Unknown

Registered

2019-11-21

Start date

2019-12-01

Completion date

Unknown

Last updated

2019-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

White matter lesions

Interventions

Cases group:none

Control group:none

Eligibility

Sex/Gender

All

Age

40 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Aged 40-80 years old; (2) cranial MRI showed definite white matter lesions; (3) systolic blood pressure >=140 and/or diastolic blood pressure >=90 mmHg.

Exclusion criteria

Exclusion criteria: (1) accompanied by mental disorders or unclear consciousness; (2) secondary hypertension; (3) a history of new acute stroke or previous history of severe stroke; (4) patients with congenital vascular disease or cerebral artery occlusion; (5) white matter lesions caused by other causes, such as multiple sclerosis, hypoxia, poisoning, etc.

Design outcomes

Primary

Measure	Time frame
Fazekas scale;Cerebral blood flow;24-hour ambulatory blood pressure;moca scale;	—

Secondary

Measure	Time frame
age;gender;BMI;blood glucose;blood lipids;	—

Countries

China

Contacts

Public ContactMingli He

The affiliated Lianyungang Hospital of Xuzhou Medical University, China

lyghml@163.com+86 18961326515

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026