Cerebral small vessel disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet the MCI diagnostic criteria; 2. aged >=60 years old; 3. informed consent, volunteer to participate.
Exclusion criteria
Exclusion criteria: 1. Hypertensive patients with uncontrollable blood pressure (systolic blood pressure greater than 160mmHg or diastolic blood pressure greater than 100mmHg); 2. have a history of alcohol and drug abuse; 3. have a history of mental illness (such as personality disorder, schizophrenia, etc.), or have severe aphasia and audio-visual disorders, or severe organ failure, history of myocardial infarction, history of coronary heart disease, musculoskeletal disorders and other contraindications; 4. cognitive impairment caused by depression, that is, the old age depression scale (ODS) >=l1; 5. people with cognitive impairment caused by drugs or poisoning; 6. are participating in other clinical trials that influence the evaluation of the results of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive state;Resting state fMRI data; | — |
Countries
China
Contacts
The Affiliated Suzhou Science & Technology Town Hospital of Nanjing Medical University