Study on the strategy of driving pressure-guided ventilaton for elderly patients undergoing major surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900027601

Enrollment

Unknown

Registered

2019-11-20

Start date

2020-01-01

Completion date

Unknown

Last updated

2019-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative complications

Interventions

Group 1:Traditional strategy of lung protective ventilation

Group 2:the strategy of Driving Pressure-guided ventilation

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) Patients and their families signed informed consent;Type of surgery (radical prostatic cancer;Radical treatment of colorectal cancer.Total cystectomy); Aged >= 65; BMI = 65; BMI < 30 kg/m2; the operation time more than 1.5 hours; Patients undergoing elective general anesthesia.

Exclusion criteria

Exclusion criteria: ASA grade is > 3; Severe pulmonary bullae; History of pneumonectomy; Preoperative CPAP or other respiratory support; Increased intracranial pressure;

Design outcomes

Primary

Measure	Time frame
Postoperative pulmonary complications;	—

Secondary

Measure	Time frame
Intraoperative hypoxemia;Intraoperative hypotension;myocardial infarction;acute kidney injury;acute hepatic failure;length of stay;ICU stay;mortality of 30 days;	—

Countries

China

Contacts

Public ContactJunran Xie

Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University

xiejunran@zju.edu.cn+86 13858126216

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026