Micro-fracture Therapy Combined with Platelet-rich Plasma injection in the Treatment of Small Sized Osteochondral Lesions of the Talus

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR1900027593

Enrollment

Unknown

Registered

2019-11-20

Start date

2019-11-11

Completion date

Unknown

Last updated

2019-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteochondral lesion of the talus

Interventions

Two groups:micro-fracture therapy combined with intra-articular injection of platelet-rich plasma (PRP) versus micro-fracture therapy alone

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. MRI results showed osteochondral lesions of the talus,and lesion area was less than 1.5square centimeters after arthroscopic debridement; 2. disease duration was greater than six months,and regular conservative treatments were ineffective; 3. Patient's lateral ankle joint without fractures,surgery,etc.; 4. patients signed informed consent.

Exclusion criteria

Exclusion criteria: 1. combined with rheumatoid arthritis,rheumatoid arthritis and autoimmune diseases; 2. combined with bleeding disorders or blood diseases; 3. combined with severe cardiovascular and cerebrovascular diseases,hypertension diabetes and malignant tumors and malignant tumors and other surgical contraindications; 4. The patient should take anticoagulant recently.

Design outcomes

Primary

Measure	Time frame
the VAS score;the AOFAS score;	—

Countries

China

Contacts

Public Contactyang Jinjie

Handan First Hospitai

280600801@qq.com+86 15333203828

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026