Apical periodontitis
Conditions
Interventions
Periapical inflammation group:No intervention
Sponsors
Nanjing Stomatological Hospital, Medical School of Nanjing University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Volunteerly participate, informed consent form be signed. 2. Aged 18-60 years. 3. Normal group: no serious systemic disease, the impacted teeth need to be removed, and the impacted teeth have no inflammation. 4. Periapical periodontitis group: had received root canal treatment, but was diagnosed with periapical periodontitis through clinical indicators and symptoms, including pre-operative apical radiographs, panoramic radiographs, conical beam CT and post-operative histological examination, and did not take antibiotics or hormone drugs for three months.
Exclusion criteria
Exclusion criteria: Normal group: patients with apical or periodontal lesions;Having a genetic history;Having received or recently received radiotherapy or chemotherapy. Periapical inflammation group: patients with autoimmune disease, cardiovascular disease, neurological disease, tumor, fever, headache, lymph node enlargement.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HIF-1a;Glucose 6-phosphate;pyruvic acid;lactic acid;hexokinase 1;NLRP3;IL-1ß; | — |
Countries
China
Contacts
Public ContactYajie Qian
Nanjing Stomatological Hospital, Medical School of Nanjing University
Outcome results
None listed