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The mechanisms of autologous bone marrow stem cells in the treatment of secondary atrophic rhinitis via migration under nasal mucosal

The mechanisms of autologous bone marrow stem cells in the treatment of secondary atrophic rhinitis via migration under nasal mucosal

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900027565
Enrollment
Unknown
Registered
2019-11-18
Start date
2019-03-01
Completion date
Unknown
Last updated
2019-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

secondary atrophic rhinitis

Interventions

Case series:BMSCs

Sponsors

Affiliated Shanghai Ninth Hospital, Shanghai Jiaotong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with secondary atrophic rhinitis typical symptoms, such as nasal congestion, hyperventilation, nasal or facial pain, nasal dryness, difficulty falling asleep, etc.; 2. Endoscopic examination revealed a wide nasal cavity with partial or complete absence of the inferior turbinate; 3. Have partial or total turbinectomy surgery histroy; 4. Nasal CT scan showed enlarged nasal cavity and inferior turbinate bone destruction; 5. General condition is good, without abnormal liver and kidney functions; 6. Conservative drug treatment for more than one year, and the effect is not good.

Exclusion criteria

Exclusion criteria: 1. In liver function, the index of gu c and gu cao exceeds 2 times of the upper limit of normal, abnormal renal function is combined with clinical symptoms or other abnormal organ function; 2. Patients with serious basic diseases, chronic diseases, hypertension and diabetes are not well controlled; 3. Those who have mental disorders or severe neurological diseases and cannot take care of themselves; 4. Pregnant or lactating women; 5. Under the age of 18 years.

Design outcomes

Primary

MeasureTime frame
Frequency of nasal mucociliary movement;acoustic rhinometry;

Secondary

MeasureTime frame
Nasal endoscopy;nasal CT scan;

Countries

China

Contacts

Public ContactShi Runjie

Affiliated Shanghai Ninth Hospital, Shanghai Jiaotong University School of Medicine

shirunjie9h@163.com+86 18616533601

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026