Bladder Cancer
Conditions
Interventions
Experimental group:Sigmoid Anterior Ureteroileal Anastomosis
Control group:Bricker ureteroileal anastomosis
Sponsors
The second hospital of anhui medical university
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years old, life expectancy is greater than or equal to 24 months; 2. Volunteer to participate in this study and sign the informed consent; 3. ECOG score of patients 0-1; 4. T2-T4a, N0-x,M0 invasive bladder cancer; High risk non-muscular invasive bladder cancer T1G3(high grade) tumor; Tis in which BCG therapy failed; Recurrent non-invasive bladder cancer; TUR and bladder perfusion were used for treatment of uncontrolled extensive papillary lesions and bladder non-urothelial carcinoma; 5. Major organ functions, such as liver, kidney, bone marrow, heart and other important organs, were not significantly abnormal: AST, ALT=25g/L; Serum creatinine (CRE)=3.5*10^9/L, neutrophils>=1.5*10^9/L, hemoglobin>=90g/L, platelets>=80*10^9/L; Left ventricular ejection fraction (LVEF) >=50%; Electrocardiogram showed no obvious abnormality or no clinical significance.
Exclusion criteria
Exclusion criteria: 1. A history of major middle and lower abdominal surgery; 2. BMI>=40kg/m2; 3. Severe cardiovascular disease; 4. History of immunodeficiency and organ transplantation; 5. History of severe central nervous system disease; 6. Failure to receive regular follow-up review as required; 7. Patients who refused to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ureteroileal Anastomosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Perioperative complications;Long-term postoperative complications; | — |
Countries
China
Contacts
Public ContactBi Liangkuan
The Second Hospital of Anhui Medical University
Outcome results
None listed