total knee arthroplasty
Conditions
Interventions
DF group:Intravenous pumping of dexmedetomidine
SF group:sciatic nerve block
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 50-80 years; 2. ASA level 2-3; 3. Subjects or family members sign informed consent voluntarily; 4. Normal ability of communication and learning.
Exclusion criteria
Exclusion criteria: 1. Knee replacement due to trauma; 2. Be allergic to dexmedetomidine and the drugs needed in the study; 3. There are contraindications to nerve block; 4. Severe bradycardia 100 min) or insufficient (<30 min) tourniquet duration; 9. serious postoperative complication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the duration of analgesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| the total dosage of sufentanil;postoperative pain score;the proportion of patients without postoperative rescue analgesia;the occurrence rate of postoperative delirium;the occurrence rate of postoperative nausea and vomiing;the occurrence rate of tourniquet-induced reponse;the first time to walk with a walker;the length of hospital stay;the dose of postoperative rescue analgesia;the dose of intraoperative vasoactive drugs;extubation time and the duration in PACU;the maintenance dose of propofol; | — |
Countries
China
Contacts
Public ContactXu Guanghong
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed