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Influence of cardiovascular risk factors on left ventricular wall motion and cardiac function in patients treated with epirubicin: a clinical study of layer-specific speckle tracking imaging

Influence of cardiovascular risk factors on left ventricular wall motion and cardiac function in patients treated with epirubicin: a clinical study of layer-specific speckle tracking imaging

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1900027545
Enrollment
Unknown
Registered
2019-11-17
Start date
2019-11-17
Completion date
Unknown
Last updated
2019-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with breast cancer under chemotherapy

Interventions

Sponsors

Department of Ultrasound Imaging, Renmin Hospital of Wuhan University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: The enrolled patients should be female and first diagnosed as breast cancer in pathology after mastectomy and lumpectomy. Before chemotherapy of epirubicin, the patients had undergone imaging tests for the exclusion of distant metastasis. All the patients receive chemotherapy with epirubicin.

Exclusion criteria

Exclusion criteria: Patients had chemotherapy, radiotherapy or endocrinotherapy before the enrollment; patients had heart failure with left ventricular ejection fraction (LVEF) less than 50%; patients with history of other malignant tumors. In addition, patients had also been excluded for lost to follow-up.

Design outcomes

Primary

MeasureTime frame
longitudinal strain;circumferential strain;SPE, SEN, ACC, AUC of ROC;SPE, SEN, ACC, AUC of ROC;

Secondary

MeasureTime frame
left ventricular ejection fraction;

Countries

China

Contacts

Public ContactBo Hu

Renmin Hospital of Wuhan University

kerisbov@126.com+86 18071099527

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026